Among contaminants of emerging concern (CEC) in water, hormones, nonylphenol and bisphenol A
has come under the spotlight in recent decade in terms of biological effect, occurences and persistency 1,2.The main analytical stream of this compounds are based on solid-phase extraction and liquid chromatography with tandem mass spectromatry (SPE-LC-MS/MS) 3,4. This proven method has been provided sensitive and reliable data. However, there are needs for improvement both sample preparation and mass spectrometry. Because conventional SPE needs large sample volume, time and labors and cartridge, there is limited monitoring data for the environment. For mass spec., target monitoring prividing accurate data, but this method cannot provide full scan information. Sometimes, additional analysis is required to obtain family group of compounds 5. For this, sample preparation of LC-MS/MS run shold be done repeatedly.
In this paper, we report a fast and accurate analytical method by online preconcentration with high
resolution / accurate mass (HR/AM) spectrometry6 for hormones, nonylphenol and bisphenol A in water.